Methyl-B12 5000

MDL043-60
$21.00
for optimal energy levels*
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Methyl B-12 is a form of the vitamin that's already in its active state, which makes it more biologically available to your body. It's important for anyone with a methylation defect to take Methyl B-12 over any of the other forms of the vitamin.

Vitamin B-12 can be obtained from your diet as two dietary forms; methylcobalamin and 5-deoxyadenosylcobalamin) via synthesis by intestinal flora and stored in the liver. These two forms are the active coenzyme forms used by human metabolism. Because our bodies contain only a very small amount of vitamin B-12 (2-5 mg), reserves can become depleted easily due to malnutrition, lack of intrinsic factor in the gut, or mal-absorption. Synthetic forms of vitamin B-12 are hydroxocobalamin and cyanocobalamin, the latter being the most widely used source in the dietary supplement industry. The liver is able to convert small amounts of cyanocobalamin into methylcobalamin; although methylcobalamin is chosen since it’s the active form and better absorbed. Research studies showing that the urinary output of methylcobalamin was far less compared to cyanocobalamin, indicating that methylcobalamin has greater tissue retention.

Methylation
Methylcobalamin is a co-enzyme in the enzyme methionine synthase which transports methyl groups for the restoration of methionine from homocysteine, along with folate (folic acid). Methionine is then utilized to create SAM-e, a donor for methyl groups, which is involved in many metabolic reactions, including the release of neurotransmitters and donating methyl groups to phospholipids. As one study has shown that adding methylcobalamin to a folic acid (folate) protocol decreases homocysteine levels quite significantly (7%) reduction).

Neurological Health
Long-term deficiency of Vitamin B-12 can affect peripheral, spinal, and cognitive nerve function, explained by methylcobalamin's role in the synthesis of the myelin sheath, the methylation of homocysteine, and the production of various neurotransmitters, such as dopamine, norepinephrine, and synephrine.

Red Blood Cell Formation
In conjunction with Folate, Vitamin B-12 is essential for the synthesis of nucleic acids and DNA synthesis during cell proliferation during their differentiation. Insufficient B-12 levels can lead to impair cell formation and increased erythroblast cell death.

Immune Health
Human research shows that Vitamin B-12 may play an important part in maintaining a healthy immune response. The research demonstrates that supplementation with Methylcobalamin with those who had inadequate B-12 levels had improved NK cell activity, and a more favorable CD4/CD8 ratio, suggesting a valuable role in cellular immunity.
 
*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Customer Reviews

Based on 14 reviews
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K
Kristen
Methyl-B12 5000

Great vitamin, easily digestible and helpful with absorption of B12 into my system.

L
LINDA DECHIARO

Methyl-B12 5000

M
Maureen Gunderson
Great

Great product

M
Maureen Gunderson
Great

Great product

C
Catherine Duggan
This was recommended by my

This was recommended by my doctor and it helps me to feel more energized and alert.

RETURNS POLICY

You have 30 calendar days to return an item from the date you received it. To be eligible for a return, your item must be unused and in the same condition that you received it. Your item must be in the original packaging. Your item needs to have the receipt or proof of purchase.

ORDER PROCESSING

Normal order processing can take between 1-3 business days (Monday – Friday)

SHIPPING

The following shipping methods are available: Standard Ground (4 – 6 business days). Flat Rate Shipping for orders below $50 is $5.95. Free shipping for orders over $50.

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You will be responsible for paying for your own shipping costs for returning your item. Shipping costs are nonrefundable. If you receive a refund, the cost of return shipping will be deducted from your refund.

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