Easy to start. Easy to cancel!

Save money while supporting sustainability! 

Our new subscription plans are on a mission to help you stay consistent with your health goals, while helping support the sustainability of the planet. 

Serrapeptase 125 Subscription (3 bottles)

$152.97 $179.97
Free shipping
Control your delivery date
Get 3 bottles every 4 months
Fewer deliveries = cleaner planet

Pause or cancel anytime after your first order


Subscription Policy
About

Serrapeptase

Serrapeptase is a proteolytic enzyme used by the Japanese silkworm to dissolve its cocoon, allowing the moth to safely escape. Due to its ability to break down nonliving proteins without harming the host, it was first discovered and used in Japan for decades for a variety of protein and mucus-related discomforts in humans.

As a dietary supplement, serrapeptase has the ability to pass through the digestive tract and circulate throughout the body to break down unwanted and damaged proteins, thereby helping to promote overall wellness.* Taken in the fasted state, it affects mucosal viscosity to improve respiratory and immune health.*

Featured reviews
Featured reviews
"I've been using this Serrapeptase for about a month now and I couldn't be happier. From the very first day I experienced clearing in my sinuses and brain fog. I've tried other brands in the past and either didn't notice much change or felt like there were more fillers than actual serrapeptase. I discovered Melanie Avalon 2 years ago. She has changed my life in many ways, to become more healthy and this supplement is no exception. I know I can trust her methodical approach and refusal to settle for anything that will have a negative impact on her audience."
— Theresa
Featured reviews
"I have just started taking the serrapeptase this week and am extremely happy. Most other supplements I cannot take on an empty stomach (I get nausea and often vomiting when I do); I have had no GI upset with Melanie's product at all…. I have now been taking your serrapeptase for around 3 weeks. I have noticed my skin has been clearer and also much less allergy symptoms (congestion, runny nose)"
— Beth
Featured reviews
So I took my first pill this morning. After fasting for about 16 hours. Oh my goodness, I can’t get over how easy I could breathe through my nose. I don’t have any nasal blockage or problems but wow, all of a sudden I could breathe through my nose with so much ease. Also, I do not know if it’s related but I lasted through my fast much longer than normal. Went to 21 hours when usually I go 18. Have no idea if that had an effect. I hope this continues and I fully appreciate total transparency Melanie uses and I think that’s why everybody trusts her so much. Thank you for your time.
— Michelle
Featured reviews
"Wow! AvalonX is more effective than any other brand of serrapeptase on the market. There was no GI discomfort like other forms I have tried and I had immediate results unlike the competitors. I would highly recommend this product for anyone who is looking to reduce inflammation. It has helped me so much in such a short period of time, it is astounding!"
— Melina

Recommended Use

As a dietary supplement, take 1 capsule up to 3 times per day on an empty stomach or as recommended by a healthcare professional. Please consult your healthcare professional before adding any health supplements to your diet.

It is recommended to wait at least 1 hour, and preferably 2 hours, before eating.

DISCLAIMER

*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Customers praised this supplement for respiratory benefits, particularly sinus relief and reduced congestion. Many reported improvements in inflammation, scar tissue, brain fog, and allergy symptoms. Shoppers appreciated the clean formulation with minimal fillers. Most take 1-2 capsules daily while fasting. One customer noted minimal effects after a month.

  • 5 stars: 138 (94%)
  • 4 stars: 5 (3%)
  • 3 stars: 4 (3%)
  • 2 stars: 0 (0%)
  • 1 star: 0 (0%)
Some of the reviews shown are from related products the merchant grouped with this one.
C
C. T. (Phoenix, AZ)
90 Capsules - 1 Bottle
So effective

This helps so much in reducing sinus and chest congestion from allergies. I didn’t know how effective it was until I ran out and was without it for a couple of weeks.

A
Anita T. (Spearfish, SD)
180 Capsules - 1 Bottle
Can’t live without it!

I’ve been taking AvalonX Serrapeptase for over a year now. My seasonal allergy symptoms are managed and I haven’t had a severe sinus infection since starting!! 🖤

D
Danielle L. (Atlanta, GA)
90 Capsules - 1 Bottle
Wow. I needed this. Who knew. thank you!!!

I wasn’t sure what to expect when I first started taking AvalonX Serrapeptase 125, but wow—this stuff works. I originally tried it to help with post-workout soreness, but I quickly noticed other benefits I hadn’t even anticipated. My sinuses? Clearer. My body? Less stiff. Even little aches I’d gotten used to just... faded.

One thing I really appreciate is how clean this supplement is. So many brands sneak in fillers or unnecessary ingredients, but this one is pure and potent without anything extra. I also love that it’s delayed-release, which seems to make a real difference in how well it works.

I’ve been taking it consistently for a while now, and it’s become a staple for me. If you deal with inflammation, sinus congestion, or just want to feel better overall, I’d definitely recommend giving it a try.

T
Tyesha M. (Short Hills, NJ)
90 Capsules - 1 Bottle

Serrapeptase 125

K
Kelly K. (Lakeview, OH)
180 Capsules - 1 Bottle
Great product

I had been diagnosed with "trigger thumb" and had already had 3 rounds of cortisone shots for relief. My physician had told me after the 3rd round, if it returned I would need surgery. I had just started intermittent fasting when I listened to Melanie Avalon talk about the benefits of taking serrapeptase and it's healing properties. I'm happy to report that after a few months my trigger thumb is GONE. I've written Melanie about this as well and have let friends/family know of the many benefits of this supplement.

L
Leticia g. (Coral Springs, FL)
90 Capsules - 1 Bottle
Love it

I have been taking this for a few months and I love how I feel.

M
Marsha P. (Columbus, OH)
180 Capsules - 1 Bottle
Serrapeptase continues as usual

I have been taking this supplement since Melanie Avalon created it. Very happy with it. I like the bigger bottle that was available in the past, but understand it was not available at this time, so was given 2 smaller bottles.

A
Annette R. (Windsor, CO)
I’m so grateful for this serrapeptase!

I’m so grateful I discovered serrapeptase. I have had two major surgeries for abdominal adhesions. My doctors had no recommendations on how to avoid a recurrence but I read a comment in an article that suggested serrapeptase could help. I have been taking two capsules per day with no side affects for five years. March 2025 will be my ten year anniversary with no episodes of adhesions!

A
Amy C. (Tower, MN)
90 Capsules - 1 Bottle
Life Changing Supplement

I now use this in place of Benadryl. It works more effectively and there are no serious side effects. I absolutely love this!!

D
Donna W. (Old Bridge, NJ)
90 Capsules - 1 Bottle
Still need more time using it

I started taking this to promote wound healing as well as allergy relief. I think it's too early to tell with the wound healing, but a nagging cough I had for MONTHS earlier this year has not returned, so I am not sure if it's a coincidence or not. One thing I can say is that when I take it in a fasted state I do notice I feel a little hungry (I do IF so I am hoping it's not producing an insulin response?) so I have been trying to take it closer to when my eating window opens (I try to do so about 2 hours beforehand).

J
JK (West Palm Beach, FL)
Serrapeptase, excellent vitamin for my heart health

Serrapeptase, excellent vitamin for my heart health. I don't know much about Microcrystalline cellulose a filler. I try to avoid many fillers as I usually react to them and try to stay vegetarian. I have not reacted to this vitamin or its fillers. I also take their ALA, and am looking now into their Probiotic.

L
Lori M. (Cincinnati, OH)
180 Capsules - 1 Bottle
LM

Love it, have my husband and sister taking it now also! Noticeably different from other name brands.

C
C. T. (Gilbert, AZ)
congestion

I can tell that the serrapeptase is making a diifference. I have less chest congestion than normal. My sinuses are also so much better than they used to be.

A
Amanda W. (Dardenne Prairie, MO)
My sinuses are thankful!

After more than a year of asking Serrapeptase, I was glad to realize I had had not one of the raging sinus infections that I routinely had 1-2 times a year. There was no denying it and I will continue to take it for this great benefit.

J
JK (West Palm Beach, FL)
180 Capsules - 1 Bottle
Serepeptase

Great product, clean ingredients. MD Logic is my newest favorite manufacturer

K
Kristy N. (Middleton, WI)
90 Capsules - 1 Bottle
Customer Service

I had questions about a product. My email was promptly answered and I was connected with the developer of the supplement.

H
Heather B. (Whitewater, WI)
90 Capsules - 1 Bottle
Loving how well it works!

Went to a subscription after the first order since I realized I could actually use just one dose. Two of us take this supplement and we both switched from another brand when we realized we only needed one dose for it to be effective. I was taking two doses of the previous brand and my SO was taking two and a half. Well worth the price!

L
Linda V. (Corona, CA)
180 Capsules - 1 Bottle
Skip triggers a shipment.

I’ve had trouble, especially serapeptase, when I skipped a shipment I ended up with an additional shipment and it happened again. I now have several bottles and huge bills. Please look at your programming. I believe the same thing happened with Magnesium 8 too. Please fix.

M
MaryJo O. (Garden City, KS)
Amazing

My sinus are much clearer now!

D
Dawn S. (Fontana, WI)
Breathing easier

So thankful I have discovered Serrapeptase 125! I am able to sleep without being woken up by a blocked nasal passage. I can breathe easier through the day as well. A lot less “gunk” in my throat. I will definitely be taking this supplement for life.

D
Deb B. (Lafayette, IN)
Makes a difference

I ran out of this supplement a couple of weeks ago and I really tell a difference as far as inflammation and sinuses.

J
Jan M. (Cashmere, WA)
90 Capsules - 1 Bottle
Pleased

My son opened our eyes to the possibility that the dead protein Amayloids could be helped with Searapeptase. Since docs say there is no cure, we seem to see noticeable improvements for my husband. We are thankful.

D
D.M. (Collierville, TN)
Sinus relief

This product is incredible. After decades of sinus congestion, this product gave me relief. Easy to take and digest. Bonus points for the glass bottle to minimize microplastics. I can absolutely tell when I have a missed a couple of days, and try very hard not to. Melanie was very particular when creating this supplement, and I am grateful.

B
Brenda T. (Seaside, CA)
180 Capsules - 1 Bottle
So far so good!

I started taking serrapeptase because of a uterine fibroid which I believe contributed to some intense symptoms. Taking the serrapeptase along with a few other changes has eliminated the symptoms I had within a month. Not sure if the Serra… was the magic bullet or a combo of all I did (more likely a combo) but understanding the benefits of the serrapeptase in general is worth taking it.

R
Ruth B. (Tampa, FL)
Finally getting a clear mammogram after a surgery that left scar tissue and No More Sinus Issues

I cannot tell you how much i LOVE Serrapeptase! In 1996 I had a benign cyst removed from my breast. Over time this caused me to have unclear mammograms. After a year of taking Serrapeptase I no longer had these issues. I believe it broke up the scar tissue at least to a degree as I no longer need 2 mammograms a year. This year has been the worst year for sinus issues in Florida and I am still free of them. I have been using Serrapeptase daily since 2020. It really works for me!

D
Darlene V.Z. (Marshalltown, IA)
180 Capsules - 1 Bottle
Game Changer

Serrapeptase has changed my life! My brain fog is gone and I credit that to serrapeptase. It has made such a huge difference and I thank Melanie and her podcast for introducing it to me!

J
Jennifer H. (Lake Ariel, PA)
180 Capsules - 1 Bottle
Serrapeptase

Love the product. Was so excited to get it. Easy to take and digest. And the glass bottle is a bonus.

K
Karen M. (Peoria, AZ)
Fibroids gone

At the onset of menopause I had three measurable uterine fibroids; six years later they are gone. I had been taking serrapeptase in an attempt to heal a scar from childhood on my forehead - the scar is still there, but the fibroids are gone. I’m going to keep taking it and I love that Melanie has pursued such a clean formulation.

W
Wendy H. (Tacoma, WA)
Working

Purchased for frozen shoulder relief and I have much improved movment