Hot flashes. Restless nights. Unexpected mood changes.
If you're navigating perimenopause or menopause, you know how unpredictable these changes can be. (Want to know more? Check out our blog post on perimenopause.)
One minute, you're perfectly comfortable. The next, you're overheating, tossing off the covers, or searching for the nearest fan.
And while menopause is a natural stage of life, that doesn't make these moments any less frustrating.
As estrogen levels fluctuate and eventually decline, your body goes through changes that can affect everything from temperature regulation and sleep to mood and overall well-being.
That's why understanding how to support your changing body matters.
One botanical that has gained attention in menopause research is Siberian rhubarb root.
And it's the source of Menofelis®, one of the key ingredients we selected for COOL, our non-hormonal approach to managing perimenopause & menopause symptoms.
What Is Menofelis® Siberian Rhubarb?
Menofelis® is a standardized botanical extract derived from the root of Siberian rhubarb (Rheum rhaponticum).
Unlike the rhubarb you might find in a pie, this plant's root contains naturally occurring compounds called rhaponticin and desoxyrhaponticin.
These compounds are particularly interesting because of how they interact with estrogen receptors in the body.
Estrogen receptors help cells respond to hormonal signals, which play important roles throughout a woman's life.
During perimenopause and menopause, fluctuating estrogen levels can influence several functions, including body temperature regulation, sleep, and mood.
What makes Siberian rhubarb unique is its natural interaction with estrogen receptor beta (ERβ).
Laboratory research has demonstrated that certain compounds found in rhapontic rhubarb interact with this receptor.
While Siberian rhubarb does not supply estrogen itself, its naturally occurring compounds have estrogen receptor activity.
The Science Behind Siberian Rhubarb and Menopause
Siberian rhubarb has a history of use in botanical wellness, and modern research has brought greater attention to its role in menopausal health.
Clinical studies using a specific standardized rhapontic rhubarb extract have reported improvements across several menopausal symptom measures.
Here's a closer look at four areas of menopause-related wellness explored in this research.
1. Hot Flashes and Temperature Comfort
Hot flashes are among the most common changes experienced during menopause. They happen when hormonal changes affect the body's ability to regulate temperature.
In a 12-week clinical trial involving 109 perimenopausal women, researchers reported significant improvements in the frequency and severity of hot flashes among participants receiving a standardized rhapontic rhubarb extract compared with placebo.
These findings have made Siberian rhubarb an important botanical of interest in menopause-focused research.
2. Night Sweats and Restful Sleep
There's nothing quite like waking up in the middle of the night feeling overheated, only to struggle to fall back asleep.
Night sweats can interrupt sleep and leave you feeling less rested the following morning.
Clinical research on standardized rhapontic rhubarb has included nighttime sweating and sleep disturbances among the menopausal symptoms assessed, with improvements reported in overall symptom scores.
And when your nights are more comfortable, getting the rest you need can become a little easier.
3. Mood and Emotional Well-Being
Feeling more irritable than usual? Finding yourself overwhelmed by things that normally wouldn't bother you?
Hormonal fluctuations during perimenopause can coincide with changes in mood and emotional well-being.
Research on standardized rhapontic rhubarb extracts has reported improvements in psychological menopausal symptom measures, including anxiety-related symptoms.
These findings add another dimension to the scientific interest in Siberian rhubarb during menopause.
4. Physical and Mental Fatigue
Sometimes, the most frustrating part of menopause isn't the hot flashes.
It's feeling tired after a full night's sleep, struggling to concentrate, or finding that everyday responsibilities require a little more effort.
Physical and mental exhaustion are also included in commonly used menopause symptom assessments.
Clinical studies of standardized rhapontic rhubarb extracts have reported improvements in these symptom measures, contributing to a broader understanding of menopause-related quality of life.
Why We Chose Menofelis® for COOL
The menopause transition can influence many aspects of everyday well-being, from temperature comfort to sleep, mood, and energy.
When developing COOL, we wanted a formula that reflected these changing needs.
Menofelis® stood out for its distinctive plant compounds and their connection to menopause-focused botanical research.
That's why we selected it alongside Black Cohosh, KSM-66® Ashwagandha, and Chasteberry in our thoughtfully formulated non-hormonal approach for perimenopause/menopause*.
Each ingredient brings something different to COOL, with the goal of complementing women's daily wellness routines through this natural transition.
Your Body Is Changing. Your Wellness Routine Can Evolve With It.
Menopause is a natural chapter of life, but that doesn't mean you have to overlook your comfort and well-being.
Whether that means prioritizing better sleep, making time for movement, managing everyday stress, or learning more about the supplements you choose, taking care of yourself matters.
Your body may be changing, but one thing shouldn't: the care you give yourself.
That's the thinking behind COOL.
Four thoughtfully selected ingredient, including Menofelis® Siberian Rhubarb, brought together in one convenient formula designed to support women's wellness during perimenopause and menopause.*
Because every chapter of life deserves your best care.
