Berberine is a natural, powerful plant alkaloid that has been used since 3000 BC, historically in Chinese and Ayurvedic medicine, for a multitude of health benefits. Today, it is best known for its potent blood sugar-regulating potential, as modern diets and lifestyles may encourage high blood sugar levels, which many experts believe is a key factor in developing metabolic syndrome and corresponding health conditions.
Berberine works through many mechanisms and is involved in a wide range of biological processes, including the regulation of glucose, lipid, and protein metabolism. It may support a healthy GI system and gut microbiome, help combat obesity by affecting fat cells and visceral adipose tissue, and help maintain a person's current healthy blood lipid status. With all of its health benefits, as well as its potential to stimulate the AMPK pathway and autophagy, and function as an antioxidant, berberine has even been proposed as an anti-aging compound.